Summary written by USA Jobs 24 from Benchling's advert and our data on 17,030 current US jobs. How we check every job
At a glance
Benchling is hiring a Software Engineer, Tools and Automation in San Francisco, CA. It is a full-time hybrid role in Software & IT, first listed on November 1. The advertised pay is $195,000–$265,000 a year. The description mentions CI/CD, Python, TypeScript, Node.js, Generative AI and Airflow. Benchling has 39 other openings in the US, 29 of them in San Francisco, CA. Across all employers on USA Jobs 24 there are 725 Software & IT openings in San Francisco, CA today; the typical one asks for 5 years and advertises about $230,000 a year at the midpoint.
How the pay compares
Benchling advertises $195,000 to $265,000 a year, a midpoint of $230,000 a year. Where an offer lands in a range usually depends on experience and on the exact location. That is higher than about 62% of the 1,317 software & IT jobs in California that publish a yearly rate on USA Jobs 24, where the typical midpoint is $213,000 a year. To see roughly what this leaves after federal and California tax, try our take-home pay calculator.
Skills in this advert
How often each skill named in this advert appears across the 4,670 software & IT jobs we list today. Python is the most widely requested (31% of jobs), while Airflow is the least common (1%). Widely requested skills are what employers expect as a baseline; rarer ones show what is special about this job.
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Before you apply
- Check it is still open. We found this job on Benchling's Ashby site on November 1 and checked it again November 4, 5:17 AM ET. When an employer takes a job down, we remove it at our next daily update.
- Plan the commute. This is a hybrid role based in San Francisco, CA. Ask how many days a week you would be expected in the office.
- Tailor your resume. Use the advert's own words, such as CI/CD, Python and TypeScript, wherever they are true for you. Our resume guide shows how.
- Know your number. Decide the lowest offer you would accept before the first call. Our salary negotiation guide explains how to ask for more.
- Apply only through Benchling's own site. Our Apply button goes straight to Benchling's Ashby page. If anyone contacts you about this job and asks for money, gift cards or bank details, stop and check it with our scam checker. Read how to spot a fake job offer.
About hiring at Benchling
Benchling has 40 openings on USA Jobs 24 today across 6 states. Most are in software & IT (13), sales & BD (9) and product & design (5). The biggest locations are San Francisco, CA (30), Boston, MA (13) and Los Angeles, CA (1). 13% of them are remote, 3% are open to entry-level candidates and 100% show pay. We collect Benchling's jobs every day straight from its own careers system (Ashby), never from job boards or agencies.
The employer's advert
This is Benchling's own description of the job, copied word for word from its careers site. We have not edited it.
Show the full advert from BenchlingHide the advert1,482 words
We are rebuilding biotech for the AI era.
When a breakthrough is delayed, the world waits. Getting a molecule from discovery to patients, or a crop from lab to field, involves thousands of slow, manual, disconnected steps. AI has the potential to change this, compressing decades of R&D work into years. But that only happens when clean, structured scientific data and AI are built into how science gets done.
Benchling is the AI platform for biotech R&D. Scientists use Benchling to design experiments, capture structured data, and run AI agents and models directly in their workflows. Over 200,000 scientists around the world trust Benchling to power their most important work, from academic labs to Sanofi, Moderna, and more than half of the world's top 50 biopharma.
We’re building an AI scientist for our customers. We can’t do that if we haven’t built the muscle ourselves. AI fluency is the foundation we build on; it's core to how we work, and we're committed to helping every new hire integrate it into their day-to-day. As part of our interview process, you'll complete a brief AI-focused exercise or discussion so we can understand how you think about and use AI to drive impact in your role. Feel free to reference any tools, platforms, or workflows you use today.
ROLE OVERVIEW
Biotechnology is rewriting life as we know it, from the medicines we take, to the crops we grow, the materials we wear, and the household goods that we rely on every day. But moving at the new speed of science requires better technology. Benchling's mission is to unlock the power of biotechnology. The world's most innovative biotech companies use Benchling's R&D Cloud to power the development of breakthrough products and accelerate time to milestone and market. Come help us bring modern software to modern science.
Benchling is building AI & Data Engineering, a small autonomous team within our Security & IT organization. AIDE owns two things: the internal AI capabilities and adoption so Benchlings can rapidly experiment and discover what works; and the source-of-truth data & analytics infrastructure the company depends on. We span the bridge between departmental AI experimentation and enterprise-grade agentic systems in production — rapidly prototyping new solutions, and graduating proven prototypes into hardened, well-governed systems with full SDLC rigor. This is an internal tools and automation role - think of it as an internal forward-deployed engineer. You will sit with the teams whose work you are automating, scope the problem with them directly, and ship the system that fixes it. AI is what we are supporting, but not directly what we build: we want someone who builds reliable internal systems and integrations, and who reaches for a model when a model is genuinely the right answer. Model research or ML engineering experience is neither required nor the bar.
We're built to be enablers. We set the patterns, standards, and shared infrastructure that let departmental teams and AI power users across the company build their own solutions, and we take on the agentic systems that no single team owns. It's early days for enterprise agentic AI at Benchling, and we'll be moving fast — iterating on prototypes, learning from internal customers, and changing direction as the field matures.
As the founding engineer for this team, you'll own the technical direction, architecture, and delivery of our internal tooling and automation portfolio. You'll be a player-coach — hands-on most of the time, leading by doing — and partner closely with our AI Product Manager on prioritization and our Data Analytics & Science team peers on the data foundations that agentic systems depend on. This is an individual contributor role on a flat team: you'll lead the engineering team in ideation, planning, and delivery and you'll drive technical hiring, while people management responsibilities sit with the hiring manager.
Check out our engineering blog for examples of past work across Benchling.
RESPONSIBILITIES
Shape technical direction and architecture: Define the foundational architecture for internal tooling and automation at Benchling - integration patterns across our SaaS estate, workflow orchestration, data access, service boundaries, and the observability that makes internal systems supportable. Where a workflow genuinely calls for an agent, own that architecture too: tool integration, state management, and evaluation. Make clear build vs. buy decisions across the stack with documented rationale.
Build and ship the early portfolio yourself: Write production code at least half your time, particularly during the team's first year. Stand up the CI/CD, testing, and deployment infrastructure the team runs on - leveraging existing patterns from Benchling's Build organization wherever possible. Graduate departmental prototypes into hardened, production-grade systems and own production support under a "you build it, you run it" model.
Design for enterprise from day one: Build for multi-tenant isolation, secrets management, audit logging, payload encryption, role-based access controls, and human-in-the-loop controls calibrated to risk. Partner with Security Engineering on threat modeling for the systems you build - including the agentic ones, where prompt injection, tool misuse, and data exfiltration are live concerns.
Enable builders across the company: Coach power users and departmental teams on production patterns, develop the criteria that decide which prototypes graduate into enterprise-grade systems, and build the internal-facing developer experience — templates, SDKs, sandboxes — that lets builders outside this team ship safely.
Partner across functions: Work closely with our data analytics peers on the source-of-truth datasets and pipelines that agentic systems depend on. Sit down with department leaders and non-technical stakeholders, turn a vague "this process is painful" into a scoped and prioritized engineering problem, and drive it to a shipped system - largely on your own judgment. Work with Benchling's platform and infrastructure teams to leverage existing capabilities rather than build parallel systems.
Elevate engineering standards: Set the bar for code quality, testing and evaluation, documentation, and on-call practices. Drive technical hiring through interview loop design, bar-raising in interviews, and representing the team to senior candidates. Mentor engineers on the team and other AI builders across the company.
QUALIFICATIONS
7+ years of professional software engineering experience building production systems, with strong systems design and integration fundamentals.
A track record of building internal tools, automation, and systems integrations that colleagues depended on daily - not customer-facing product work alone. You have wired together APIs, SaaS platforms, and internal services, and you owned the result in production.
Demonstrated understanding of how to optimize workloads across deterministic and non-deterministic capabilities, striking the right architectural balance for the needs of the specific solution being implemented.
Production experience with at least two of: Python, TypeScript/Node.js, Go; comfort with working across the stack.
Practical experience applying LLMs where they earn their place in a workflow - and the judgment to recognize where they do not. We care that you shipped something that worked and that people kept using, not which framework you reached for.
Track record of going from zero to one: a platform, function, or product area you built up from scratch and scaled.
Experience operating in regulated or security-sensitive environments. Solid grasp of enterprise security fundamentals — encryption, access controls, audit logging, secrets management.
Comfortable exercising technical leadership independent of positional authority. You set direction, raise the bar in design reviews, and grow other engineers through influence.
Build software with a product-first approach. You ship code quickly and care about the real-world impact of your work.
Enjoy ownership and building key pieces of platforms.
Strong communication skills with non-technical audiences specifically. You can sit with a finance, legal, or sales ops team, understand their workflow well enough to challenge it, and come back with an engineering plan they recognize as their own problem - then explain the tradeoffs in their language.
Interest in learning more about life science (prior knowledge is not required).
NICE TO HAVE
Background in enterprise SaaS, life sciences, or biotech.
Familiarity with LLM orchestration and tool-integration patterns (MCP, agent SDKs from major model providers).
Experience with async orchestration (Temporal, Prefect, Airflow) applied to long-running or agentic workflows.
Familiarity with SOC 2, HIPAA, or GxP compliance as they apply to AI systems.
Experience building internal developer platforms or internal tools at scale.
Direct experience coaching or enabling non-engineers (analysts, ops staff, business power users) to build with AI tooling.
Model research or ML engineering.
HOW WE WORK
We offer a flexible hybrid work arrangement that prioritizes in-office collaboration. Employees are expected to be on-site 3 days per week (Monday, Tuesday, and Thursday).
#LI-Hybrid
#BI-Hybrid
#LI-CG1
Benchling welcomes everyone.
We believe diversity enriches our team so we hire people with a wide range of identities, backgrounds, and experiences.
We are an equal opportunity employer. That means we don’t discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status. We also consider for employment qualified applicants with arrest and conviction records, consistent with applicable federal, state and local law, including but not limited to the San Francisco Fair Chance Ordinance.
USA Jobs 24 copied this listing from Benchling's official careers site on November 1, 2026 and checked it again November 4, 5:17 AM ET. Benchling will never ask you to pay to apply or to buy equipment with a check they send you. If anyone does, it is a scam.
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