Summary written by USA Jobs 24 from AstraZeneca's advert and our data on 17,030 current US jobs. How we check every job
At a glance
AstraZeneca is hiring a Product Line Lead, Clinical & Agentic AI in Boston, MA. It is a full-time role in Healthcare & Life Sciences, first listed on November 1. The advertised pay is $181,570–$272,356 a year. The description mentions Generative AI and Jira. AstraZeneca has 99 other openings in the US, 12 of them in Boston, MA. Across all employers on USA Jobs 24 there are 38 Healthcare & Pharma openings in Boston, MA today; the typical one asks for 5 years and advertises about $194,000 a year at the midpoint.
How the pay compares
AstraZeneca advertises $181,570 to $272,356 a year, a midpoint of $226,963 a year. Where an offer lands in a range usually depends on experience and on the exact location. That is higher than about 63% of the 56 healthcare & pharma jobs in Massachusetts that publish a yearly rate on USA Jobs 24, where the typical midpoint is $215,000 a year. To see roughly what this leaves after federal and Massachusetts tax, try our take-home pay calculator.
Skills in this advert
How often each skill named in this advert appears across the 650 healthcare & pharma jobs we list today. Generative AI is the most widely requested (3% of jobs), while Jira is the least common (1%). Widely requested skills are what employers expect as a baseline; rarer ones show what is special about this job.
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Before you apply
- Check it is still open. We found this job on AstraZeneca's Workday site on November 1 and checked it again November 4, 5:17 AM ET. When an employer takes a job down, we remove it at our next daily update.
- Check the location works for you. This role is based in Boston, MA. If you would need to move, ask whether relocation help is offered.
- Tailor your resume. Use the advert's own words, such as Generative AI and Jira, wherever they are true for you. Our resume guide shows how.
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About hiring at AstraZeneca
AstraZeneca has 100 openings on USA Jobs 24 today across 15 states. Most are in healthcare & pharma (26), sales & BD (12) and marketing (9). The biggest locations are Boston, MA (13), Philadelphia, PA (2) and Seattle, WA (1). None of them is fully remote, 14% are open to entry-level candidates and 71% show pay. We collect AstraZeneca's jobs every day straight from its own careers system (Workday), never from job boards or agencies.
The employer's advert
This is AstraZeneca's own description of the job, copied word for word from its careers site. We have not edited it.
Show the full advert from AstraZenecaHide the advert1,167 words
About AISI
AI Strategy & Innovation (AISI) sits at the centre of AstraZeneca's R&D AI transformation. Our remit is to build, buy and deliver the AI models and agents that change pipeline outcomes, across discovery, translational science, biomarkers and clinical development.
Role Summary
AstraZeneca is building agentic AI products that take work out of clinical development and clinical operations, starting with automating site-monitoring reports and data review for clinical research associates. We are seeking a Product Line Lead, Clinical & Agentic AI, to own the product line that takes these agents from proof of concept to GxP-validated use, and to set the direction of the agentic AI platform layer that supports them.
You will lead product ownership across the line, including the product owner for the clinical research associate (CRA) agent, and set priorities, lifecycle gates and decision rights between product and engineering. You will make sure each product is built with the data access, human oversight and validation evidence that regulated clinical settings require, from the start. You will also guide how the platform layer evolves as enterprise AI assistants take on more of AstraZeneca's everyday agentic work, including which use cases still need a purpose-built, governed platform because of patient data.
You will work with clinical development and operations leaders, AI scientists and engineers, R&D IT, Enterprise AI platform teams, Quality, and external delivery partners. This line is early in its life and the platform landscape is changing. We are looking for someone who is decisive, comfortable with ambiguity, and credible with both clinical and engineering audiences.
Accountabilities:
Product Line Strategy and Roadmap
- Define and own the strategy, roadmap and success measures for the clinical and agentic AI product line, tied to AISI's must-win outcomes and the multi-year plan.
- Decide what to start, scale, merge or stop across the line, using clear lifecycle gates and evidence of value.
- Define and maintain decision rights between product and engineering (product decides what and why; engineering decides how), and make them hold in practice.
- Keep one current view of the line's portfolio, funding, cost and risk, and report on it to AISI leadership.
Leading Product Owners and Delivery
- Direct and develop the product owners on the line, starting with the CRA agent product owner. Make sure every product has an accountable owner, a roadmap, a backlog and a value case.
- Work with engineering leaders and external delivery partners to clear blockers, including data access, environments and integration dependencies.
- Set the operating rhythm (planning, reviews, stage gates) so that delivery scales as the line grows.
Clinical Agentic Products
- Own the path of the CRA agent from proof of concept through silent pilot to GxP-validated release, including sign-off from business owners across therapeutic and operational areas.
- Translate clinical operations needs into product requirements and measurable outcomes, such as monitoring effort saved and trial capacity gained.
- Make human-in-the-loop design, auditability and validation planning product requirements from the first release.
Agentic Platform Direction
- Set the product direction for the agentic platform layer used by R&D, and recommend where to build, buy, adopt or retire platforms.
- Define and defend the boundary for patient data and regulated use: which use cases need a governed, purpose-built platform, and which can run on enterprise assistants.
- Lead the transition plan and user communications when platforms change, working with Enterprise AI and IT partners.
Governance, Compliance and Quality
- Work with Quality, Compliance and Data Privacy so that products meet GxP computerised system validation, data privacy and AI governance requirements.
- Own the line's risk register and raise issues early, including security findings and control gaps.
- Support audit and inspection readiness for the line's products and processes.
Financial and Vendor Stewardship
- Keep cost visible across headcount, contractors, cloud compute and model usage, and contribute to planning cycles.
- Manage vendor and outsourced delivery partners to agreed scope, quality and cost.
Cross-Functional Collaboration
- Build strong relationships with clinical development and operations leaders, AISI science teams, Enterprise AI and R&D IT.
- Communicate clearly about readiness, trade-offs and uncertainty so that leaders can make decisions.
Essential Skills/Experience:
Education
- At least a Master's degree or PhD in life sciences, data science, computer science, engineering or a related field. An advanced degree is desirable.
Experience
- 10 or more years of experience in product management or product leadership, including leading other product owners or managers.
- Experience in pharmaceutical, biotechnology or other regulated healthcare technology settings.
- Track record of taking a product from proof of concept to validated production use in a regulated environment.
- Working knowledge of clinical development or clinical operations processes, such as site monitoring and clinical data review.
- Familiarity with agentic and LLM-based products, and with how to evaluate their quality and risk.
- Understanding of GxP computerised system validation and data privacy requirements.
- Experience managing budgets and outsourced delivery partners.
- Proven ability to make and communicate prioritisation decisions across senior stakeholders.
Desirable Skills/Experience:
- Experience with clinical systems such as EDC and CTMS.
- Experience with platform product management and build, buy or adopt decisions.
- Working knowledge of Atlassian tools (JIRA, Confluence).
The annual base pay (or hourly rate of compensation) for this position ranges from $181,570.4 to $ 272,355.6 USD. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.
AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing AZCHumanResources@astrazeneca.com.
Why AstraZeneca:
Join a place where you are trusted to take ownership and move fast, combining scientific rigor with data-driven operations to deliver therapies that change lives. You will work shoulder-to-shoulder with unexpected teams in the same room, unleashing bold thinking to solve complex logistics challenges at scale. We champion curiosity and decisive action, value kindness alongside ambition, and empower you with the tools, partnerships, and freedom to shape how living medicines reach patients across the world.
Call to Action:
Lead the global nerve center of cell therapy logistics and build the systems, teams, and partnerships that move cures to patients faster—bring your expertise and make your mark.
Where can I find out more?
- Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
- Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
- Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
- Our US Footprint: Powering Scientific Innovation - YouTube
#LI-Hybrid
Date Posted
30-Oct-2026Closing Date
29-Nov-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.
USA Jobs 24 copied this listing from AstraZeneca's official careers site on November 1, 2026 and checked it again November 4, 5:17 AM ET. AstraZeneca will never ask you to pay to apply or to buy equipment with a check they send you. If anyone does, it is a scam.
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