Summary written by USA Jobs 24 from Amgen's advert and our data on 17,030 current US jobs. How we check every job
At a glance
Amgen is hiring a Director, Clinical Pharmacology, Modeling and Simulation in South San Francisco, CA. It is a full-time role in Healthcare & Life Sciences, asking for at least 4 years of experience, first listed on November 3. Amgen has 99 other openings in the US, 1 of them in South San Francisco, CA.
How the pay compares
Amgen has not published pay for this job, or we could not find it in the advert. Of the 92 healthcare & pharma jobs in California on USA Jobs 24, 86% show pay, and the typical yearly midpoint among them is $234,000. That gives you a fair starting point when the subject comes up. California has a pay transparency law that requires most employers to give a pay range for jobs there, so it is reasonable to ask the recruiter for it.
Before you apply
- Check it is still open. We found this job on Amgen's Workday site on November 3 and checked it again November 4, 5:17 AM ET. When an employer takes a job down, we remove it at our next daily update.
- Check the location works for you. This role is based in South San Francisco, CA. If you would need to move, ask whether relocation help is offered.
- Match the experience. The advert asks for at least 4 years of experience. If you are a little short, a close match on the skills in the advert can still win an interview.
- Apply only through Amgen's own site. Our Apply button goes straight to Amgen's Workday page. If anyone contacts you about this job and asks for money, gift cards or bank details, stop and check it with our scam checker. Read how to spot a fake job offer.
About hiring at Amgen
Amgen has 100 openings on USA Jobs 24 today across 34 states. Most are in sales & BD (50), healthcare & pharma (8) and software & IT (8). The biggest locations are Thousand Oaks, CA (14), Phoenix, AZ (6) and Chicago, IL (5). 17% of them are remote, 4% are open to entry-level candidates and 30% show pay. We collect Amgen's jobs every day straight from its own careers system (Workday), never from job boards or agencies.
The employer's advert
This is Amgen's own description of the job, copied word for word from its careers site. We have not edited it.
Show the full advert from AmgenHide the advert1,161 words
Career Category
ResearchJob Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
Director, Clinical Pharmacology, Modeling and Simulation
What you will do
Let’s do this. Let’s change the world. The Clinical Pharmacology, Modeling & Simulation Department at Amgen is seeking a Director at its South San Francisco, CA location. In this vital role you will be responsible for the development and implementation of the Clinical Pharmacology, Modeling & Simulations strategies for the industry leading cutting-edge pipeline of most innovative therapeutic modalities. Amgen’s robust pipeline leverages state-of-the-art science and molecular engineering focused on the pursuit of transformative medicines with large effects in serious diseases.
The Director, Clinical Pharmacology, Modeling & Simulation will be a leader in the field of clinical pharmacology and a Subject Matter Expert. You will be an expert in designing strategic clinical pharmacology, modeling & simulations plans integrated with clinical development plans in support of new drug development across modalities. You will have expertise in designing clinical pharmacology and biopharmaceutic studies. You will be an expert in clinical drug development and will apply Model-Informed Drug Development (MIDD) strategies and approaches together with principles of quantitative clinical pharmacology to ensure optimal drug development. You will represent the Clinical Pharmacology, Modeling & Simulation Department at the global cross-functional drug development teams. You will apply innovative Quantitative Pharmacokinetic/Pharmacodynamic (PK/PD) approaches and clinical pharmacology strategies and principles to guide optimal drug development across early to late-stage development programs. Your expertise will include application of Population PK/PD modeling, Physiologically Based Pharmacokinetic (PBPK) modeling, and Quantitative Systems Pharmacology (QSP) modeling to new drug development to ensure development of safe & effective dosing regimens for various patient sub-populations & ensure optimal new drug development.
What you will do
We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications.
Basic Qualifications:
Doctorate degree and 4 years of Clinical Pharmacology and Modeling & Simulation experience
OR
Master’s degree and 8 years of Clinical Pharmacology and Modeling & Simulation experience
OR
Bachelor’s degree and 10 years of Clinical Pharmacology and Modeling & Simulation experience
In addition to meeting at least one of the above requirements, you must have at least 4 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above
Preferred Qualifications:
- PhD (in Pharmacokinetics or Pharmaceutical Sciences or Pharmacology or equivalent professional degrees e.g. MD, PharmD).
- 8+ years of experience in Clinical Pharmacology, Modeling & Simulation in the Biotechnology/Pharmaceutical Industry.
- Established track-record of designing strategic clinical pharmacology, modeling & simulations plans in support of new drug development across modalities.
- Experience in leading the design and implementation of clinical pharmacology and biopharmaceutic studies including bioequivalence, bio-comparability, drug-drug interaction, special population, ethnic sensitivity, ADME and pediatric studies and integrating results into regulatory filings, and product labels.
- Established track-record of interaction with global health authorities, authoring regulatory documents, knowledge of global regulatory requirements and guidance
- Hands-on experience in Quantitative Pharmacokinetic/Pharmacodynamic (PK/PD) approaches with a focus on Population PK/PD modeling, Physiologically Based Pharmacokinetic (PBPK) modeling to inform clinical study designs for drug-drug interaction, special population, ethnic sensitivity, pediatric and biopharmaceutics studies. Expert knowledge of commonly used software for PBPK modeling required.
- Established track-record of Model Based Drug Development.
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.
The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.
In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
- A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
- A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
- Stock-based long-term incentives
- Award-winning time-off plans
- Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.
Apply now and make a lasting impact with the Amgen team.
careers.amgen.com
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Application deadline
Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.
Sponsorship
Sponsorship for this role is not guaranteed.
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
Amgen will consider for employment qualified applicants with criminal histories in a manner consistent with the San Francisco Fair Chance Ordinance.Salary Range
216,414.25USD -292,795.75 USDUSA Jobs 24 copied this listing from Amgen's official careers site on November 3, 2026 and checked it again November 4, 5:17 AM ET. Amgen will never ask you to pay to apply or to buy equipment with a check they send you. If anyone does, it is a scam.
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